Comparison of three rat strains for development of radiation-induced lung injury after hemithoracic irradiation

Authors
van Eerde, MR Kampinga, HH Szabo, BG Vujaskovic, Z
Citation
Mr. Van Eerde et al., Comparison of three rat strains for development of radiation-induced lung injury after hemithoracic irradiation, RADIOTH ONC, 58(3), 2001, pp. 313-316
Citations number
26
Categorie Soggetti
Radiology ,Nuclear Medicine & Imaging","Onconogenesis & Cancer Research
Journal title
RADIOTHERAPY AND ONCOLOGY
ISSN journal
01678140 → ACNP
Volume
58
Issue
3
Year of publication
2001
Pages
313 - 316
Database
ISI
SICI code
0167-8140(200103)58:3<313:COTRSF>2.0.ZU;2-F
Abstract
The purpose of this study is to define differences in radiation sensitivity among rat strains using breathing frequency and lung perfusion as end poin ts of radiation-induced lung injury. The results have confirmed previous fi ndings in mice showing that-under stringently controlled iso-dose/volume ir radiation conditions, substantial differences can be found in susceptibilit y to functional lungs damage after radiation. (C) 2001 Elsevier Science ire land Ltd. All rights reserved.