O. Tenaillon et al., Second-order selection in bacterial evolution: selection acting on mutation and recombination rates in the course of adaptation, RES MICROB, 152(1), 2001, pp. 11-16
The increase in genetic variability of a population can be selected during
adaptation, as demonstrated by the selection of mutator alleles. The dynami
cs of this phenomenon, named second-order selection, can result in an impro
ved adaptability of bacteria through regulation of all facets of mutation a
nd recombination processes, (C) 2001 Editions scientifiques et medicales El
sevier SAS.