Enantioselective borane reduction of aromatic ketones catalyzed by chiral aluminum alkoxides

Authors
Fu, IP Uang, BJ
Citation
Ip. Fu et Bj. Uang, Enantioselective borane reduction of aromatic ketones catalyzed by chiral aluminum alkoxides, TETRAHEDR-A, 12(1), 2001, pp. 45-48
Citations number
11
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON-ASYMMETRY
ISSN journal
09574166 → ACNP
Volume
12
Issue
1
Year of publication
2001
Pages
45 - 48
Database
ISI
SICI code
0957-4166(20010205)12:1<45:EBROAK>2.0.ZU;2-3
Abstract
The asymmetric borane reduction of prochiral ketones with an alkoxide catal yst prepared in situ from aluminum tri-iso-propoxide and (R)-binaphthol was examined. Using these conditions, alcohols were obtained in high yield and e.e.'s of up to 83%. (C) 2001 Published by Elsevier Science Ltd. All right s reserved.