Conventional thyroidectomy often leaves an undesirable scar on the anterior
neck. The aim of this study was to assess the feasibility and efficacy of
endoscopic thyroidectomy, a new minimally invasive technique for thyroid su
rgery. Between September 1998 and February 2000, 18 patients with a solitar
y thyroid nodule wtderwent endoscopic thyroidectomy utilizing CO2 insufflat
ion. There were 16 females and 2 males with a mean age of 43 years (range 1
7-66 years), indications for surgery included indeterminate cytology (n = 8
), follicular neoplasm (n = 8), Hurthle cell neoplasm (n = 1), and toxic th
yroid nodule (n = 1). The mean nodule diameter was 2.7 cm (0.6-7 cm). Analg
esic requirement, return to normal activity, and cosmetic results were comp
ared to 18 consecutive patients who had conventional thyroidectomy. Sixteen
of 18 cases were successfully completed endoscopically with a mean operati
ng time of 220 minutes (range, 120-330 minutes). There were no major compli
cations, but 3 patients developed mild hypercarbia and 1 patient had an inc
idental parathyroidectomy. When compared to conventional thyroidectomy, pat
ients undergoing endoscopic thyroidectomy had a significantly superior cosm
etic result (p < 0.005) and a quicker return to normal activity (p < 0.05),
but there was no difference in analgesic requirement. Endoscopic thyroidec
tomy is a technically feasible and safe procedure that leads to an improved
cosmetic result and a quicker recovery. Open completion thyroidectomy is r
ecommended for thyroid carcinoma until more data are available.