The economics of vaccinating restaurant workers against hepatitis A were st
udied using Monte Carlo simulation models, one with a restaurant-owner pers
pective, and one with a societal perspective. The restaurant model allowed
for a different size, number of employees and employee turnover rate. Benef
its were the avoidance of loss of business (including the possibility of ba
nkruptcy) after publicity linking the restaurant to an outbreak associated
with a case of hepatitis A in a food handler. Additional benefits in the so
cietal model included reductions in costs of food handler-associated cases
of hepatitis A. The outcome used was Net Present Value (NPV), allowing comp
arison between models. Regardless of the cost of vaccination ($50-140/emplo
yee), for a restauranteur to ensure that all employees were vaccinated at a
ll times substantial costs were involved (i.e. negative NPV). Even a 75% pr
obability of bankruptcy still resulted in negative NPVs at the 95th percent
iles. For society, vaccination was only cost-saving (i.e. positive NPV) if
done only during epidemics and if it cost < $20/employee. Vaccinating resta
urant employees is unlikely to be economical from either the restaurant own
er or the societal perspective, even during hepatitis A epidemics. Publishe
d by Elsevier Science Ltd.