The mycotoxin fumonisin B-1 (FB1) causes a variety of health problems in an
imals, while epidemiological evidence suggests it is linked to human esopha
geal cancer. We investigated the carry-over of FB1 into bovine milk using t
he isolated perfused bovine udder. Two mg of FB(1)was injected into the per
fusion blood of 3 udders, and milk and perfused serum levels were determine
d for 150 min. FB1 passed through the mammary barrier into the milk, but in
such low concentrations as to present a negligible risk for consumers.