Fluorescence decay time distribution analysis of cyclic enkephalin analogues; Influence of solvent and Leu configuration in position on conformation

Authors
Malicka, J Ganzynkowicz, R Groth, M Czaplewski, C Karolczak, J Liwo, A Wiczk, W
Citation
J. Malicka et al., Fluorescence decay time distribution analysis of cyclic enkephalin analogues; Influence of solvent and Leu configuration in position on conformation, ACT BIOCH P, 48(1), 2001, pp. 95-102
Citations number
28
Categorie Soggetti
Biochemistry & Biophysics
Journal title
ACTA BIOCHIMICA POLONICA
ISSN journal
0001527X → ACNP
Volume
48
Issue
1
Year of publication
2001
Pages
95 - 102
Database
ISI
SICI code
0001-527X(2001)48:1<95:FDTDAO>2.0.ZU;2-4
Abstract
Lifetime distribution analysis were performed to study the influence of Leu configuration in position 5 on changes of the peptide chain of cyclic anal ogues of enkephalins containing a fluorescence donor and acceptor in differ ent solvents. The configuration change of Leu5 in all the analogues of enke phalins studied which contain donor-acceptor pairs has no apparent influenc e on Trp lifetime distributions, In contrast, there is a significant solven t effect on the shape of lifetime distribution.