Loose anagen hair syndrome: a familial case with fetal hair in the meconium

Introduction. Loose anagen hair syndrome is a recently described hair disor der. We report a familial case. Case report, Two sisters were examined, 4 years-old and 8 months old, from a consanguineous marriage, At birth, they presented diffuse alopecia of the scalp; the meconium contained black and silky hair. Clinical examination n oted the short, fine hair with easy and painless uprooting. No clinical ass ociated symptoms were observed. The trichogram showed 70 p. too of anagen h air and 30 p. too of telogen hairs. Discussion, Our familial case is original by this clinical symptom: dischar ge of probably dystrophic foetal hair in the meconium. Loose anagen hair is characterised by easily pluckable hair. The trichogram confirms the diagno stic. It is composed of anagen hairs (80 to 100 p. 100) devoid of sheaths. The loose anagen hair is usually isolated, but associations have been repor ted. It may occur in families. The precise pathogenesis and treatment of th is hair disorder are not known.