Nonpigmenting solitary fixed drug eruption after skin testing and intra-articular injection of triamcinolone acetonide

Background: Although several medications have been reported to cause fixed drug eruption (FDE) reactions, triamcinolone acetonide has not been previou sly described as an offending agent. Objective: To emphasize both an unprecedented causative agent and the extra ordinary development of a FDE, we describe this response in a 42-year-old f emale patient. Methods: Because her history included a questionable reaction to corticoste roid preparations, prick and intradermal testing with triamcinolone acetoni de was done to determine whether she could safely receive a triamcinolone a cetonide injection. Results: Both skin test procedures and the intra-articular administration o f triamcinolone acetonide caused FDEs on her right retroauricular area. Conclusions: Because any drug may induce a FDE by any administration route, physicians should be aware of this delayed skin reaction when skin testing drugs.