We describe four cases of eosinophilic cystitis in whom no specific cause c
ould be found, and review the literature. Complaints at presentation includ
ed urgency, frequency, abdominal pain, and haematuria. In three patients th
e symptoms and ultrasound pictures suggested a bladder tumour. One patient
was treated with anticholinergics and corticosteroids without relief of sym
ptoms; a localised eosinophilic tumour was excised in one patient who remai
ned symptom free; and two patients were managed conservatively with spontan
eous resolution of bladder pathology and symptoms. One case was identified
by random bladder biopsy in 150 consecutive patients with unexplained irrit
able micturition complaints. Eosinophilic cystitis is rare in children. Aft
er biopsy, we consider a wait and see policy is justified as symptoms tend
to disappear spontaneously. Routine bladder biopsies in children with unexp
lained bladder symptoms is not justifiable.