Of the vitamins tested, inositol was the most effective for erythritol prod
uction. To increase erythritol production by Torula sp., inositol and a rel
ated compound, phytic acid (myoinositol hexaphosphate), were added to the c
ulture media. Erythritol production in the presence of phytic acid was grea
ter than that in the presence of inositol, due to the synergistic effects o
f phosphate and inositol. Supplementation with phosphate and inositol incre
ased cell growth, erythritol production, and the activity of erythrose redu
ctase in cells. Inositol was a more effective stimulator of cell growth and
erythritol production than was phosphate.