Case of lipoblastoma with two derivative chromosomes 8 containing homogeneously staining-like regions and a review of the literature: lipoblastoma and chromosome 8

Authors
Batanian, JR Brink, DS Thorpe, CM Haddad, BR
Citation
Jr. Batanian et al., Case of lipoblastoma with two derivative chromosomes 8 containing homogeneously staining-like regions and a review of the literature: lipoblastoma and chromosome 8, CANC GENET, 125(1), 2001, pp. 10-13
Citations number
22
Categorie Soggetti
Onconogenesis & Cancer Research
Journal title
CANCER GENETICS AND CYTOGENETICS
ISSN journal
01654608 → ACNP
Volume
125
Issue
1
Year of publication
2001
Pages
10 - 13
Database
ISI
SICI code
0165-4608(200102)125:1<10:COLWTD>2.0.ZU;2-1
Abstract
We report a case of a lipoblastoma in a 10-month-old girl in which the cyto genetic aberration showed a homogeneously staining-like region (hsr) within two derivative chromosomes 8. There was a loss of one normal copy of chrom osome 8 and gain of two identical derivative chromosomes 8 with the karyoty pe designation 47,XX,psu idic(s)(pter --> q12 similar to 13::hsr::q12 simil ar to 13 --> pter), +psu idic (8)(pter --> q12 similar to 13::hsr::q12 simi lar to 13 --> pter). This is the first report of a chromosomal aberration o f this type seen in lipoblastoma. (C) 2001 Elsevier Science Inc. All rights reserved.