M. Di Serio et al., A kinetic and mass transfer model to simulate the growth of baker's yeast in industrial bioreactors, CHEM ENGN J, 82(1-3), 2001, pp. 347-354
A structured unsegregated cybernetic model, able to simulate the growth of
baker's yeast in any possible condition in multistage industrial production
has been developed. The model has first been proven in the simulation of t
he behavior of a laboratory batch bioreactor, describing the evolution with
time of the biomass growth rate, the glucose and oxygen consumption as wel
l as the production of ethanol and carbon dioxide. The same model with the
same parameters has then been used to simulate both laboratory and industri
al size fed-batch bioreactors achieving satisfactory results. The effect of
the oxygen mass transfer Limitation in fed-batch bioreactors has also been
described and discussed. The model developed allows to find and keep the o
ptimal conditions of biomass growth in industrial fed-batch bioreactors. (C
) 2001 Elsevier Science B.V. All rights reserved.