Macrocyclic saccharide bundles as a new type of firm DNA binders

Authors
Hayashida, O Matsuo, A Aoyama, Y
Citation
O. Hayashida et al., Macrocyclic saccharide bundles as a new type of firm DNA binders, CHEM LETT, (3), 2001, pp. 272-273
Citations number
9
Categorie Soggetti
Chemistry
Journal title
CHEMISTRY LETTERS
ISSN journal
03667022 → ACNP
Issue
3
Year of publication
2001
Pages
272 - 273
Database
ISI
SICI code
0366-7022(20010305):3<272:MSBAAN>2.0.ZU;2-G
Abstract
Double helical DNAs such as plasmid DNA pBR322 and calf thymus (CT) DNA wer e firmly bound to calix[4]resorcarene-based saccharide bundles, as demonstr ated by the electrophoretic, circular dichroism (CD) spectroscopic, dynamic light scattering, and thermal-stability criteria. The long-chain cluster c ompound inter acts with DNAs more effectively than a shorter one.