Lessons learned from statin trials

This article aims to review lessons learned about lipid lowering and statin s in the past decade and to consider what developments the future may hold. Results from a series of landmark clinical trials confirm that statins sig nificantly reduce cardiovascular morbidity and mortality in patients with a nd without previous coronary artery disease. The potential of this drug cla ss has yet to be fully explored. Studies currently under way will answer ma ny of the outstanding questions.