Surgical intervention and fracture repair are usually achieved without comp
lication. Although there are numerous methods of enhancing fracture repair,
the addition of a bone graft is most commonly used. Many biologic and biop
hysical alternatives exist that may accelerate the natural healing process
and be used to treat complications such as delayed union or nonunion fractu
res. Many of these treatment modalities are currently being used in human o
rthopedic surgery.