RNA-based silencing strategies in plants

Authors
Matzke, MA Matzke, AJM Pruss, GJ Vance, VB
Citation
Ma. Matzke et al., RNA-based silencing strategies in plants, CUR OP GEN, 11(2), 2001, pp. 221-227
Citations number
57
Categorie Soggetti
Cell & Developmental Biology
Journal title
CURRENT OPINION IN GENETICS & DEVELOPMENT
ISSN journal
0959437X → ACNP
Volume
11
Issue
2
Year of publication
2001
Pages
221 - 227
Database
ISI
SICI code
0959-437X(200104)11:2<221:RSSIP>2.0.ZU;2-Z
Abstract
In plants, double-stranded RNA can silence genes by triggering degradation of homologous RNA in the cytoplasm and by directing methylation of homologo us nuclear DNA sequences. Analyses of Arabidopsis mutants and plant viral s uppressors of silencing are unraveling RNA-silencing mechanisms, which requ ire common proteins in diverse organisms, and are assessing the role of met hylation in transcriptional and posttranscriptional gene silencing.