Lyme disease in central Europe

Lyme borreliosis is a fascinating disease, the aetiopathology of which is n ot yet completely known. Different subspecies of Borrelia burgdorferi sensu late are responsible for the variable clinical course of the disease. Some new cutaneous (alopecia) and ocular (photophobia and retinal vasculitis) m anisfestations have been described and the largest prospective study on ery thema migrans during pregnancy was published during the last year. Optimal therapy of Lyme borreliosis is still lacking, but doxycycline, amoxicillin, penicillin, and ceftriaxone are recommended most frequently. Curr Opin Inf ect Dis 14:133-137. (C) 2001 Lippincott Williams & Wilkins.