Studies have found that coping strategies are significant predictors o
f pain report, health care use, and psychosocial adjustment in childre
n with sickle cell disease (SCD); however; the mechanisms of the relat
ionship are not cleat: In this study, 41 children with SCD completed a
laboratory pain task to analyze their pain perception under standardi
zed conditions. Sensory decision theory analyses were used to analyze
the pain perception data. Children and their parents also completed me
asures of coping strategies and adjustment Hierarchical regression ana
lyses controlling for the child's age indicated that children who repo
rted using active cognitive and behavioral coping strategies had a low
er tendency to report pain during the laboratory pain task Results are
discussed in terms of the utility of using laboratory pain models wit
h children and the need for future intervention studies to target copi
ng strategies in children with SCD pain.