Cystic hygroma colli as the first echographic sign of the fetal akinesia sequence

We report first trimester cystic hygroma colli with subsequent resolution a nd development of a fetal akinesia deformation sequence. Neuropathological examination of the brain showed intra- and extracellular white matter edema while spinal cord, peripheral nerves and muscles were normal. Hygroma coll i as the first echographic sign of subsequent severe fetal akinesia sequenc e without muscular dystrophy as seen in the Lethal Multiple Pterygium syndr ome has not been previously reported.