Quinoline alkaloids of Orixa japonica

Research works on the isolation, classification, biosynthesis, and biologic al activities of quinoline alkaloids from Orixa japonica (Rutaceae), done m ainly by these authors, are reviewed. 1. Introduction 2. The isolation of quinoline alkaloids from Orixa japonica 3. Biosynthesis of the quinoline alkaloids 4. Investigation of the absolute stereochemistry of an important biosynthet ic intermediate, (-)-preorixine 5. Antimalarial activity of the quinoline alkaloids 6. Rat small intestine muscle relaxation activity of the quinoline alkaloid s 7. Conclusion