In the 21st century, new vaccines are likely to be the products of molecula
r biology Manipulation of genes, transcripts, and proteins will facilitate
the generation of immune responses. In some cases the genes will be carried
by attenuated vectors. However classic methods of vaccine development will
continue to be fruitful. The vaccination schedule will be more complicated
, although there will be fewer injections owing to the development of combi
nation Vaccines and greater use of nonparenteral routes.