Recent progress in matrix-assisted laser desorption ionization postsource decay

In matrix-assisted laser desorption and ionization mass spectrometry, using a time-of-flight analyzer, decomposition of analytes by postsource decay c an be examined by making use of an electrostatic ion reflector, thus record ing tandem mass spectra. In recent years reasonable progress has been made using different instrument configurations and different types of reflectors . Also, the resolution of the first mass spectrum, i.e. the resolution of t he precursor ion selector and the speed and possibility of automation of th e acquisition and interpretation of the data has been improved. This articl e reviews the work of different groups working in this held and discusses t he advantages of various arrangements. (Int J Mass Spectrom 206 (2001) 275- 286) (C) 2001 Elsevier Science B.V.