The biology of dust mites and the remediation of mite allergens in allergic disease

In most temperate humid areas of the world, house dust mites are a major so urce of multiple allergens in house dust Mite allergens sensitize and induc e perennial rhinitis, asthma, or atopic dermatitis in a large portion of pa tients with allergic disease. There is convincing evidence that avoidance o f mite allergen can effectively reduce allergic symptoms, Patients can be m oved to a mite allergen-free environment, or mite and mite allergen abateme nt can be performed to reduce exposure in existing residences. Some knowled ge of the biology of house dust mites is essential to understand the basis of the recommendations for reducing mites and mite allergens in homes and t o appreciate the difficulty of eliminating house dust mites and mite allerg ens from homes. This article reviews key aspects of the biology of dust mit es, the properties of mite allergens, recommendations for reducing mite and mite allergen concentrations in homes, and practical recommendations for t reatment.