The most popular measure of tobacco dependence, the Fagerstrom Tolerance Qu
estionnaire (FTQ), measures only tobacco-specific behaviors. In contrast, t
he most popular assessment of addiction among polydrug users is the Addicti
on Severity Index (ASI). Most of the subscales comprising the ASI are psych
osocial measures, not drug-specific measures. A study was undertaken to com
pare the predictive utility of these two contrasting measures. The NAS (ada
pted from the FTQ) and the Addiction Severity Index (ASI),were used to pred
ict future smoking status in a cohort of polydrug users followed annually f
or 3 years. The baseline NAS score explained more of the variance in Time 2
and Time 3 smoking status than did the ASI subscales. When previous smokin
g status was included as a covariate, however, the NAS no longer predicted
future smoking status, whereas the ASI Subscales continued to explain signi
ficant variance in future smoking status. Results suggest that when past sm
oking behavior is known, a respondent's legal status and alcohol use may be
more useful than a measure of tobacco dependence for predicting future smo
king status