A preliminary investigation of the solution complexation of 4-sulphonic calix[n]arenes with testosterone

Authors
Millership, JS
Citation
Js. Millership, A preliminary investigation of the solution complexation of 4-sulphonic calix[n]arenes with testosterone, J INCL P MA, 39(3-4), 2001, pp. 327-331
Citations number
22
Categorie Soggetti
Chemistry
Journal title
JOURNAL OF INCLUSION PHENOMENA AND MACROCYCLIC CHEMISTRY
ISSN journal
13883127 → ACNP
Volume
39
Issue
3-4
Year of publication
2001
Pages
327 - 331
Database
ISI
SICI code
1388-3127(200104)39:3-4<327:APIOTS>2.0.ZU;2-W
Abstract
The complexation between water soluble calixarenes and testosterone has bee n studied. Stability constants of the host guest complexes of 4-sulphonic c alix[n]arenes (n = 4, 6 and 8) with testosterone in water and buffers (pH 5 .8, 7.3 and 10.0) were determined from phase solubility curves. These solub ility curves indicated that the complexes were all of the A(L) type. The co nstants were in the range 26-341 M-1, dependent on the size of the calixare ne and the pH of the solutions.