SEQUENCE-ANALYSIS OF THE 33 KB LONG REGION BETWEEN ORC5 AND SUI1 FROMTHE LEFT ARM OF CHROMOSOME-XIV FROM SACCHAROMYCES-CEREVISIAE

We have determined the nucleotide sequence of a chromosomal region of 33,016 bp located on the left arm of chromosome XIV from budding yeast between the ORC5 and the SUI1 gene. Subsequent sequence analysis reve aled the presence of 18 non-overlapping open reading frames (ORFs) inc luding eight previously identified and sequenced genes (ORC5, ATX1, SI P3, NRD1, RAD50, MPA43, RPA49 and SUI1). Three other ORFs (YNL256w, YN L255c and YNL247w) code for putative proteins with significant homolog y to proteins from other organisms, while 4 ORFs exhibit only weak hom ology to known proteins. Three ORFs have no homology with sequences in the databases. The sequences have been deposited in the EMBL database under Accession Number X96722. (C) 1997 by John Wiley & Sons, Ltd.