Deprotonation of hydrochloride salts of amino acid eaters and peptide esters using commercial zinc dust

Authors
Ananda, K Babu, VVS
Citation
K. Ananda et Vvs. Babu, Deprotonation of hydrochloride salts of amino acid eaters and peptide esters using commercial zinc dust, J PEPT RES, 57(3), 2001, pp. 223-226
Citations number
18
Categorie Soggetti
Biochemistry & Biophysics
Journal title
JOURNAL OF PEPTIDE RESEARCH
ISSN journal
1397002X → ACNP
Volume
57
Issue
3
Year of publication
2001
Pages
223 - 226
Database
ISI
SICI code
1397-002X(200103)57:3<223:DOHSOA>2.0.ZU;2-T
Abstract
The deprotonation of hydrochloride salts of ethyl and methyl esters of amin o acids and peptides is accomplished using activated zinc dust. The reactio n is neat and quantitative. Thus, the free amino acid esters and peptide es ters have been isolated in good yield and purity.