Posttransplant primary cutaneous T-cell lymphoma

A patient with posttransplant cutaneous lymphoma is described. Although mos t posttransplant lymphomas are of B-cell origin, this patient's lymphoma is a primary cutaneous lymphoma of T-cell origin. Another report exists of: t he first case of posttransplant primary cutaneous T-cell lymphoma localized to the lower extremities. Our patient's involvement was generalized with t umor nodules on the face and anterior chest. Reduced immune surveillance, c hronic antigenic stimulation caused by transplant grafts, and the direct on cogenic effects of immunosuppressive drugs have all been suggested as mecha nisms. Prompt recognition of this condition and initiation of appropriate t herapy with reduction of high-dose immunosuppression can lead to better pat ient outcomes.