Background: The purpose of the study was to analyze if perceptual voice qua
lity ratings of the well-known RBH rating procedure (a 4-point scale of rou
ghness, breathiness, and hoarseness) covary with acoustical voice parameter
s. Methods: 120 voice samples from subjects with healthy and hoarse voices
were rated on the RBH-index in a multicenter study with 31 raters. Multivar
iate regression tree analysis classified the perceptual ratings as "gold st
andard". Voice samples were acoustically analyzed with a feature extraction
method, Feedforward-networks were trained to selected acoustical parameter
s having highest "relative importance" in the regression trees. Based on th
e best classifier, a computer program consisting of 50 simultaneous working
networks was developed. Results: Mean probabilities for correct classifica
tions were found at 0.65-0.85, implying a significance level over chance (0
.25). Classifications of the program matched in 40% with a priori values in
the categories roughness combined with breathiness, and in 65% in at least
one domain. Conclusions: The new method described here provides a psychoac
oustically based "objective" classification of hoarse voices, which seems t
o enable future analysis of new parameters (like GNE), which may even impro
ve the present results.