The genomic revolution is undeniable: in the past year alone, the term 'gen
omics' was found in nearly 500 research articles, and at least 6 journals a
re devoted solely to genomic biology. More than just a buzzword, molecular
biology has genuinely embraced genomics (the systematic, large-scale study
of genomes and their functions). With its facile genetics, the budding yeas
t Saccharomyces cerevisiae has emerged as an important model organism in th
e development of many current genomic methodologies. These techniques have
greatly influenced the manner in which biology is studied in yeast and in o
ther organisms. In this review, we summarize the most. promising technologi
es in yeast genomics.