The brainweb: Phase synchronization and large-scale integration

Citation
F. Varela et al., The brainweb: Phase synchronization and large-scale integration, NAT REV NEU, 2(4), 2001, pp. 229-239
Citations number
124
Categorie Soggetti
Neurosciences & Behavoir
Journal title
NATURE REVIEWS NEUROSCIENCE
ISSN journal
14710048 → ACNP
Volume
2
Issue
4
Year of publication
2001
Pages
229 - 239
Database
ISI
SICI code
1471-0048(200104)2:4<229:TBPSAL>2.0.ZU;2-S
Abstract
The emergence of a unified cognitive moment relies on the coordination of s cattered mosaics of functionally specialized brain regions. Here we review the mechanisms of large-scale integration that counterbalance the distribut ed anatomical and functional organization of brain activity to enable the e mergence of coherent behaviour and cognition. Although the mechanisms invol ved in large-scale integration are still largely unknown, we argue that the most plausible candidate is the formation of dynamic links mediated by syn chrony over multiple frequency bands.