Antiinflammatory and antioxidant property of saponins of tea [Camellia sinensis (L) O. Kuntze] root extract

Authors
Sur, P Chandhuri, T Vedasiromoni, JR Gomes, A Ganguly, DK
Citation
P. Sur et al., Antiinflammatory and antioxidant property of saponins of tea [Camellia sinensis (L) O. Kuntze] root extract, PHYTOTHER R, 15(2), 2001, pp. 174-176
Citations number
13
Categorie Soggetti
Pharmacology & Toxicology
Journal title
PHYTOTHERAPY RESEARCH
ISSN journal
0951418X → ACNP
Volume
15
Issue
2
Year of publication
2001
Pages
174 - 176
Database
ISI
SICI code
0951-418X(200103)15:2<174:AAAPOS>2.0.ZU;2-A
Abstract
Two groups of saponins, TS-1 and TS-2, isolated from tea root extract (TRE) were tested for antiinflammatory and in vitro antioxidant activity. Both T S-1 and TS-2 inhibited carrageenan-induced paw oedema in rats. The antioxid ant activity of these compounds was evaluated using the xanthine-xanthine o xidase system. The study indicated that the previously observed antitumour activity of TRE might be mediated through scavenging of free radicals by sa ponins and their antiinflammatory activity. Copyright (C) 2001 John Whey & Sons, Ltd.