We report the case of a patient presenting a subacute, predominantly sensor
y neuropathy. The work up revealed a Sjogren's syndrome and a breast carcin
oma. The presence of anti-nu antibodies, identified by Western Blot using p
urified recombinant HuD protein, and the absence of the Hu antigen in the b
reast carcinoma ruled out the responsibility of the Sjogren's syndrome or b
reast carcinoma. In this context, the most likely diagnosis was a subacute
neuropathy associated with small cell lung cancer, which was indeed discove
red 3 years later.