A 53-year-old man was evaluated for snoring, dysphagia for solid foods and
difficulty of breathing and a polysomnographic recording was consistent wit
h a diagnosis of obstructive sleep apnoea syndrome (OSAS). A flexible fiber
optic bronchoscopy (FFB) showed the presence of a nodular lesion of the pos
terior ventral surface of the tongue strictly connected to the left lateral
border of the epiglottis. The biopsy specimen taken from the lesion was co
nsistent with sarcoidosis. No involvement of pulmonary parenchyma, lymph no
des or other organs was recognized. After two months of steroid treatment,
symptoms disappeared and resolution of the nodular lesion at the FFB and no
rmalization of the polysomnographic recording were observed. This is the fi
rst report of orolaryngeal sarcoidosis associated with OSAS as the only cli
nical presentation of the disease.