Investigation of the synthesis of angular tricyclic compounds by intramolecular Pauson-Khand reaction of exo- and endo-cyclic enynes

Authors
Ishizaki, M Iwahara, K Niimi, Y Satoh, H Hoshino, O
Citation
M. Ishizaki et al., Investigation of the synthesis of angular tricyclic compounds by intramolecular Pauson-Khand reaction of exo- and endo-cyclic enynes, TETRAHEDRON, 57(14), 2001, pp. 2729-2738
Citations number
63
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON
ISSN journal
00404020 → ACNP
Volume
57
Issue
14
Year of publication
2001
Pages
2729 - 2738
Database
ISI
SICI code
0040-4020(20010402)57:14<2729:IOTSOA>2.0.ZU;2-V
Abstract
Intramolecular Pauson-Khand reaction of various alkynyl exo-alkylidene-cycl ohexanes and -pentane gives angular type 6-5-5 and 5-5-5 tricyclic compound s in good to high yield. The present reaction also offers convenient constr uction of two contiguous quaternary centers, which could not be synthesized from alkynyl endo-cycloolefins. Scope and limitation of the present reacti on of various exo- and endo-cyclic enynes are also described. (C) 2001 Else vier Science Ltd. All rights reserved.