Synthesis of 6-aryl-2,4-diamino-pyrimidines and triazines using palladium catalysed Suzuki cross-coupling reactions

Authors
Cooke, G de Cremiers, HA Rotello, VM Tarbit, B Vanderstraeten, PE
Citation
G. Cooke et al., Synthesis of 6-aryl-2,4-diamino-pyrimidines and triazines using palladium catalysed Suzuki cross-coupling reactions, TETRAHEDRON, 57(14), 2001, pp. 2787-2789
Citations number
10
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON
ISSN journal
00404020 → ACNP
Volume
57
Issue
14
Year of publication
2001
Pages
2787 - 2789
Database
ISI
SICI code
0040-4020(20010402)57:14<2787:SO6ATU>2.0.ZU;2-H
Abstract
The high yielding synthesis of 6-aryl-2,4-diaminopyrimidines and triazines via palladium catalysed Suzuki cross-coupling reactions of commercially ava ilable 6-chloro-2,4-diaminopyrimidine 1 or 6-chloro-2,4-diaminotriazine 8 a nd aryl boronic acids are described. (C) 2001 Elsevier Science Ltd. All rig hts reserved.