Model studies on total synthesis of the chartellines, spirocyclic beta-lactam alkaloids from a marine bryozoan

Citation
Xc. Lin et Sm. Weinreb, Model studies on total synthesis of the chartellines, spirocyclic beta-lactam alkaloids from a marine bryozoan, TETRAHEDR L, 42(14), 2001, pp. 2631-2633
Citations number
19
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
42
Issue
14
Year of publication
2001
Pages
2631 - 2633
Database
ISI
SICI code
0040-4039(20010402)42:14<2631:MSOTSO>2.0.ZU;2-A
Abstract
A chartelline alkaloid model system containing a spirocyclic beta -lactam m oiety and alpha,beta -unsaturated imine has been constructed from isatin us ing a Staudinger imine-ketene cycloaddition and an addition to an N-activat ed gamma -lactam as key steps. (C) 2001 Elsevier Science Ltd. All rights re served.