From early 1999 onwards, cattle health problems accompanied by chronic wast
ing of unknown aetiology were reported on a number of dairy farms. An assoc
iation between these health problems and the compulsory use of gE-negative
marker vaccines against bovine herpesvirus 1 was presumed by farmers. On on
e dairy farm an increased milk production of 50% was reported within a few
days after parenteral vitamin B-12 treatment. Therefore, the current study
was designed to determine the effect of parenteral vitamin B-12 treatment o
n the milk production of diary herds with wasting cattle.
A randomized blind trial was performed in five problem herds and two contro
l herds. On each farm five lactating cows were injected intramuscularly wit
h 20 mg vitamin B-12 and paired with five untreated lactating cows. The mil
k production of treated and untreated animals was measured for 19 days foll
owing treatment and compared to pre-treatment production.
No effect of vitamin B-12 treatment on milk production was established on e
ither problem farms or control farms. Neither was a difference detected in
the response to vitamin B-12 treatment between problem herds and control he
rds.
In a second experiment, parenteral vitamin B-12 treatment was applied in th
ree problem herds by local veterinary practitioners. The results of this ex
periment were in line with the results of the first experiment.