The prevalence of asthma in children has increased 160 percent since 1980,
and the disease currently affects nearly 5 million children in the United S
tates. The National Asthma Education and Prevention Program provides guidel
ines for improved asthma care. The goals of this program are to limit the f
requency, severity and costliness of asthma exacerbations through extensive
education of physicians, children and caregivers. The four components of a
sthma management include regular assessment and monitoring, control of fact
ors that contribute to or aggravate symptoms, pharmacologic therapy and edu
cation of children and their caregivers. The guidelines recommend a stepwis
e approach to pharmacologic treatment, starting with aggressive therapy to
achieve control and followed by a "step down" to the minimal therapy that w
ill maintain control. Quick relief of symptoms can be achieved preferential
ly by the use of short-acting beta, agonists. Medications for long-term con
trol should be considered for use in children with persistent symptoms. Inh
aled corticosteroids are the most potent long-term anti-inflammatory medica
tions. Other options include long-acting beta, agonists, cromolyn sodium an
d nedocromil, antileukotriene agents and theophylline. All have advantages
and disadvantages in individual situations.