Effect of red wine and ethanol on production of nitric oxide in healthy subjects

Authors
Matsuo, S Nakamura, Y Takahashi, M Ouchi, Y Hosoda, K Nozawa, M Kinoshita, M
Citation
S. Matsuo et al., Effect of red wine and ethanol on production of nitric oxide in healthy subjects, AM J CARD, 87(8), 2001, pp. 1029
Citations number
7
Categorie Soggetti
Cardiovascular & Respiratory Systems","Cardiovascular & Hematology Research
Journal title
AMERICAN JOURNAL OF CARDIOLOGY
ISSN journal
00029149 → ACNP
Volume
87
Issue
8
Year of publication
2001
Database
ISI
SICI code
0002-9149(20010415)87:8<1029:EORWAE>2.0.ZU;2-0
Abstract
Direct analysis of nitric oxide (NO) has been a difficult task owing to its instability and low concentration in tissues.' However, a new selective fl uorescent indicator, diaminofluoresceins (DAF-2), enabled the direct detect ion of NO under physiologic conditions.(2,3) This study was performed to cl arify the acute effect of red wine, ethanol, and polyphenol on the producti on of NO and oxidative stress in healthy subjects.