Effect of American ginseng extract (Panax quinquefolius) on formalin-induced nociception in mice

lTwenty-three ICR mice were force fed orally with American ginseng extract, Panax quinquefolius, (Cold FX(R)) for 4 days. Another 20 mice were fed wit h water as placebo in a similar fashion. Formalin tests which yield typical ly two phases of pain behavior were done in both groups. Although there was no difference in the first phase between groups, mice treated with Cold FX (R) spent significantly less time in licking and biting of the injured paws in the second phase. The data indicate that American ginseng may have anal gesic effect in this chronic pain model.