We present a case of a previously well 24-year-old female patient who devel
oped severe and life-threatening Irukandji syndrome that required ventilati
on and inotropic support. This case provides further evidence that there ar
e jellyfish other than the Irukandji jellyfish that can cause cardiac decom
pensation, and there is a suggestion that application of a pressure immobil
ization bandage may worsen the envenomation. We include our recommended tre
atment for the Irukandji syndrome.