Water-soluble arsenic residues from several arsenolipids occurring in the tissues of the starspotted shark Musterus manazo

Alkali-labile and alkali-stable arsenolipid fractions were prepared from 12 tissues of the starspotted shark Musterus manazo and analyzed by high-perf ormance liquid chromatography-inductively coupled mass spectrometry, At lea st six arsenolipids were found in the shark. Two major alkali-labile arseno lipids (a dimethylated arsenic-containing lipid and an arsenocholine-contai ning lipid) were shown in ordinary muscle, dark muscle, heart, bone, skin a nd stomach, whereas a single major arsenolipid, the dimethylated arsenic-co ntaining lipid, was shown in the intestine, liver, kidney, spleen and brain . Besides these lipids, four other minor alkali-labile arsenolipids were pr esent. On the other hand, as for the alkali-stable arsenolipids, a dimethyl ated arsenic-containing lipid and an arsenocholine-containing lipid were al so found in dark muscle, skin, stomach and intestine, whereas only dimethyl ated arsenic-containing lipid was found in the liver. Copyright (C) 2001 Jo hn Wiley & Sons, Ltd.