Relationship between alcohol consumption, ambulatory blood pressure recordings and left ventricular mass

Citation
J. Ryan et al., Relationship between alcohol consumption, ambulatory blood pressure recordings and left ventricular mass, BLOOD PRESS, 10(1), 2001, pp. 22-26
Citations number
11
Categorie Soggetti
Cardiovascular & Respiratory Systems
Journal title
BLOOD PRESSURE
ISSN journal
08037051 → ACNP
Volume
10
Issue
1
Year of publication
2001
Pages
22 - 26
Database
ISI
SICI code
0803-7051(2001)10:1<22:RBACAB>2.0.ZU;2-H
Abstract
The relationship between alcohol consumption, blood pressure and left ventr icular mass remains uncertain. A detailed alcohol intake history, clinic bl ood pressure measurements, 24-h ambulatory blood pressure recordings and me asurements of left ventricular mass using magnetic resonance imaging (MRI) were performed in 98 males aged 47.9 +/- 9.7 years, 20 of whom were receivi ng antihypertensive monotherapy. Alcohol consumption (median intake 315 g/w eek, range 0-2050) was significantly related to supine systolic clinic bloo d pressures (beta = 0.20, p = 0.05) but not to clinic supine diastolic bloo d pressures (beta = 0.12, p = 0.25), 24-h blood pressures (systolic: B = -0 .03, p = 0.75; diastolic beta = -0.05, p = 0.60), awake blood pressures or sleeping blood pressures. Alcohol consumption was not related to left ventr icular mass index (B = -0.05, p = 0.59). Left ventricular mass was strongly related to mean 74-h systolic blood pressures (beta = 0.28, p = 0.01), mea n awake and sleeping systolic blood pressures, and less strongly to clinic systolic blood pressures (beta = 0.23, p = 0.03). These results were not si gnificantly altered by adjusting for age, smoking, body mass index or alcoh ol intake, or by excluding the 20 men who were receiving antihypertensive t herapy. The results of this study suggest that alcohol consumption at level s commonly encountered in the community is not an important predictor of le ft ventricular mass index in men, either via direct effects or by indirect effects on blood pressure.