To increase the ability of ultrasonographic (US) technology for the differe
ntial diagnosis of solid breast tumors, we describe a novel computer-aided
diagnosis (CADx) system using data mining with decision tree for classifica
tion of breast tumor to increase the levels of diagnostic confidence and to
provide the immediate second opinion for physicians. Cooperating with the
texture information extracted from the region of interest (ROI) image, a de
cision tree model generated from the training data in a top-down, general-t
o-specific direction with 24 co-variance texture features is used to classi
fy the tumors as benign or malignant. In the experiments, accuracy rates fo
r a experienced physician and the proposed CADx are 86.67% (78/90) and 95.5
0% (86/90), respectively.