Serum cholesteryl ester transfer protein concentrations in healthy Chinesesubjects and cardio-cerebrovascular disease patients

Serum cholesteryl ester transfer protein (CETP) concentration was measured in 1128 healthy Chinese subjects using a "sandwich" enzyme immunoassay and was 1.84 +/- 1.55 mg/l (mean +/-S.D.). The frequency distribution of CETP i n healthy subjects was markedly skewed towards low concentrations. The CETP concentration in females was significantly higher than that in males (2.40 +/-1.65 mg/l vs. 1.49 +/-1.37 mg/l, P<0.001). Then was a weak inverse corr elation between the CETP concentration and age (r=-0.19, P<0.001). The CETP concentrations were significantly higher in 117 myocardial infarction (MI) survivors and 110 stroke patients than that in 335 healthy, age-matched ma les (1.98 +/-1.68 173 +/-1.45, and 1.40 +/-1.37 mg/l respectively, P<0.01), while no relation was found between CETP concentration and lipids concentr ation in MI, stroke and healthy group. <(c)> 2001 Published by Elsevier Sci ence B.V.