H. Nutahara et al., A simple computerized program for the calculation of the required sample size necessary to ensure statistical accuracy in medical experiments, COMPUT M PR, 65(2), 2001, pp. 133-139
We developed a sample size estimation program (SSEP) with which medical res
earchers can easily estimate the appropriate sample size for a specific sig
nificance level and statistical power using their favorite WWW browsers. SS
EP can estimate the sample sizes for six statistical methods by Monte-Carlo
simulation: Student's I-test, Welch's t-test, Analysis of valiance, Wilcox
on's rank sum test, Kruskal-Wallis test, and the Cochran-Armitage test for
linear trends. The SSEP simulation programs were created using the SAS soft
ware macro language. Medical researchers can interactively use this program
and determine reliable sample sizes when planning new prospective clinical
studies and animal experiments. (C) 2001 Elsevier Science Ireland Ltd. All
rights reserved.