THE ENEMIES WITHIN - INTERGENOMIC CONFLICT, INTERLOCUS CONTEST EVOLUTION (ICE), AND THE INTRASPECIFIC RED-QUEEN

Different loci within the genome of a single species can potentially c oevolve in a manner that is analogous to the Red Queen process among s pecies. The major factor driving this antagonistic coevolution among l oci is intergenomic conflict, i.e., discord between individuals that i s mediated by two or more gene products that are derived from differen t gene loci. We conclude that antagonistic coevolution is common among loci that code for social interactions, and that it has broad evoluti onary implications, especially in the context of speciation and sex ch romosome evolution.