Subcutaneous phaeohyphomycotic cysts caused by Exophiala jeanselmei in a lung transplant patient

BACKGROUND. Phaeohyphomycosis is a skin fungal infection caused by dematiac eous fungi that often affects immunocompromised patients, Local recurrence after medication or surgical treatment is common in these patients, We pres ent a case in which a 42-year-old woman status postbilateral lung transplan t developed phaeohyphomycotic cysts with local recurrence and then was succ essfully treated by local excision with pre- and postsurgery oral itraconaz ole treatment, OBJECTIVE. TO demonstrate the utility of pre- and postsurgery oral itracona zole in immunocompromised patients with recurrent phaeohyphomycosis. METHODS. Local excision with pre- and postsurgery oral itraconazole treatme nt, RESULTS. Simple excision or excision with postsurgery oral itraconazole res ulted in local recurrence in this patient. Local excision with pre- and pos tsurgery oral itraconazole was effective in preventing the local recurrence . CONCLUSION. Phaeohyphomycosis can run a prolonged course in immunocompromis ed patients with multiple recurrences, Local excision with pre- and postsur gery oral itraconazole can be used to treat these patients with recurrent p haeohyphomycosis.